Speed-dependent cellular decision making in nonequilibrium genetic circuits.

Despite being governed by the principles of nonequilibrium transitions, gene expression dynamics underlying cell fate decision is poorly understood. In particular, the effect of signaling speed on cellular decision making is still unclear. Here we show that the decision between alternative cell fate...

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Bibliographic Details
Main Authors: Nuno R Nené, Jordi Garca-Ojalvo, Alexey Zaikin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3302799?pdf=render