Re-definition and supporting evidence toward Fanconi Anemia as a mitochondrial disease: Prospects for new design in clinical management

Re-definition and supporting evidence toward Fanconi Anemia as a mitochondrial disease: Prospects for new design in clinical management

Fanconi anemia (FA) has been investigated since early studies based on two definitions, namely defective DNA repair and proinflammatory condition. The former definition has built up the grounds for FA diagnosis as excess sensitivity of patients’ cells to xenobiotics as diepoxybutane and mitomycin C,...

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Bibliographic Details
Main Authors: Giovanni Pagano, Luca Tiano, Federico V. Pallardó, Alex Lyakhovich, Sudit S. Mukhopadhyay, Paolo Di Bartolomeo, Adriana Zatterale, Marco Trifuoggi
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Redox Biology
Subjects:
Clastogens
Prooxidant state
Mitochondrial dysfunction
Mitochondrial disease
Mitochondrial nutrients
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231721000082

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http://www.sciencedirect.com/science/article/pii/S2213231721000082

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