General rules for optimal codon choice.

Different synonymous codons are favored by natural selection for translation efficiency and accuracy in different organisms. The rules governing the identities of favored codons in different organisms remain obscure. In fact, it is not known whether such rules exist or whether favored codons are cho...

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Bibliographic Details
Main Authors: Ruth Hershberg, Dmitri A Petrov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2700274?pdf=render