Multistability in the epithelial-mesenchymal transition network

Abstract Background The transitions between epithelial (E) and mesenchymal (M) cell phenotypes are essential in many biological processes like tissue development and cancer metastasis. Previous studies, both modeling and experimental, suggested that in addition to E and M states, the network respons...

Full description

Bibliographic Details
Main Authors: Ying Xin, Bree Cummins, Tomáš Gedeon
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-020-3413-1