Liver regeneration signature in hepatitis B virus (HBV)-associated acute liver failure identified by gene expression profiling.

Liver regeneration signature in hepatitis B virus (HBV)-associated acute liver failure identified by gene expression profiling.

The liver has inherent regenerative capacity via mitotic division of mature hepatocytes or, when the hepatic loss is massive or hepatocyte proliferation is impaired, through activation of hepatic stem/progenitor cells (HSPC). The dramatic clinical course of acute liver failure (ALF) has posed major...

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Bibliographic Details
Main Authors: Oriel Nissim, Marta Melis, Giacomo Diaz, David E Kleiner, Ashley Tice, Giovanni Fantola, Fausto Zamboni, Lopa Mishra, Patrizia Farci
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3504149?pdf=render

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http://europepmc.org/articles/PMC3504149?pdf=render

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