Near-infrared uncaging or photosensitizing dictated by oxygen tension

The generation of reactive oxygen species (ROS) in photodynamic cancer treatments is limited by low intraturmoural oxygen availability. Here the authors show that irradiation of a silicon phthalocyanine leads to uncaging of a biologically active molecule or to ROS formation in an oxygen-dependent ma...

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Bibliographic Details
Main Authors: Erin D. Anderson, Alexander P. Gorka, Martin J. Schnermann
Format: Article
Language:English
Published: Nature Publishing Group 2016-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms13378