GDF15 secreted by senescent endothelial cells improves vascular progenitor cell functions.

Endothelial dysfunction (ED) is part of the first steps in the development of cardiovascular diseases (CVD). Growth Differentiation Factor 15 (GDF15) is a cytokine belonging to the Transforming Growth Factor β superfamily and its expression is increased both during ED and in CVD. Because high blood...

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Bibliographic Details
Main Authors: Guillaume Ha, Fanny De Torres, Nassim Arouche, Nassima Benzoubir, Ségolène Ferratge, Elie Hatem, Adrienne Anginot, Georges Uzan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0216602