Induced neural progenitor cells abundantly secrete extracellular vesicles and promote the proliferation of neural progenitors via extracellular signal–regulated kinase pathways

Induced neural progenitor cells abundantly secrete extracellular vesicles and promote the proliferation of neural progenitors via extracellular signal–regulated kinase pathways

Neural stem/progenitor cells (NPCs) are known to have potent therapeutic effects in neurological disorders through the secretion of extracellular vesicles (EVs). Despite the therapeutic potentials, the numbers of NPCs are limited in the brain, curbing the further use of EVs in the disease treatment....

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Bibliographic Details
Main Authors: Yizhao Ma, Kaizhe Wang, Jiabin Pan, Zhaohuan Fan, Changhai Tian, Xiaobei Deng, Kangmu Ma, Xiaohuan Xia, Yunlong Huang, Jialin C. Zheng
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Neurobiology of Disease
Subjects:
Cellular reprogramming
Neural progenitor cells
Extracellular vesicles
Proliferation
Growth factors
ERK pathways
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996118307575

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http://www.sciencedirect.com/science/article/pii/S0969996118307575

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