Calreticulin is a Critical Cell Survival Factor in Malignant Neoplasms.

Calreticulin (CRT) is a high-capacity Ca2+ protein whose expression is up-regulated during cellular transformation and is associated with disease progression in multiple types of malignancies. At the same time, CRT has been characterized as an important stress-response protein capable of inducing im...

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Bibliographic Details
Main Authors: Arum Han, Chen Li, Tara Zahed, Michael Wong, Ian Smith, Karl Hoedel, Douglas Green, Alexander D Boiko
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-09-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000402