Prediction of “Aggregation-Prone” Peptides with Hybrid Classification Approach

Protein aggregation is a biological phenomenon caused by misfolding proteins aggregation and is associated with a wide variety of diseases, such as Alzheimer’s, Parkinson’s, and prion diseases. Many studies indicate that protein aggregation is mediated by short “aggregation-prone” peptide segments....

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Bibliographic Details
Main Authors: Bo Liu, Wenyi Zhang, Longjia Jia, Jianan Wang, Xiaowei Zhao, Minghao Yin
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Mathematical Problems in Engineering
Online Access:http://dx.doi.org/10.1155/2015/857325