MP470, a novel receptor tyrosine kinase inhibitor, in combination with Erlotinib inhibits the HER family/PI3K/Akt pathway and tumor growth in prostate cancer
<p>Abstract</p> <p>Background</p> <p>Prostate cancer is a common disease in men and at present there is no effective therapy available due to its recurrence despite androgen deprivation therapy. The epidermal growth factor receptor family (EGFR/HER1, HER2/neu and HER3)/...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-05-01
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Series: | BMC Cancer |
Online Access: | http://www.biomedcentral.com/1471-2407/9/142 |