MP470, a novel receptor tyrosine kinase inhibitor, in combination with Erlotinib inhibits the HER family/PI3K/Akt pathway and tumor growth in prostate cancer

<p>Abstract</p> <p>Background</p> <p>Prostate cancer is a common disease in men and at present there is no effective therapy available due to its recurrence despite androgen deprivation therapy. The epidermal growth factor receptor family (EGFR/HER1, HER2/neu and HER3)/...

Full description

Bibliographic Details
Main Authors: Croce Kimiko, Riley Christopher, Stejskal Amy, Cooke Larry S, Qi Wenqing, Saldanha Jose W, Bearss David, Mahadevan Daruka
Format: Article
Language:English
Published: BMC 2009-05-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/142