THE DEVELOPMENT OF HYPERTENSIVE NEURORETINOPATHY MODEL ON WISTAR RATS

A model of hypertensive neuroretinopathy was developed on Wistar line rats with administration of non-selective NO-synthase blocker N-nitro-L-arginine methyl ester (L-NAME) in a dose 12.5 mg/kg within 28 days on the background of single increased intraocular pressure (IOP) to 110 mmHg. As a result o...

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Bibliographic Details
Main Authors: Anna Peresypkina, Alexandr Dolzhikov, Viktoriya Gubareva, Elena Levkova, Anna Shabelnikova
Format: Article
Language:English
Published: Pensoft Publishers 2017-03-01
Series:Research Results in Pharmacology
Subjects:
las
Online Access:https://rrpharmacology.pensoft.net/article/31046/download/pdf/