Antibody degradation in tobacco plants: a predominantly apoplastic process

<p>Abstract</p> <p>Background</p> <p>Interest in using plants for production of recombinant proteins such as monoclonal antibodies is growing, but proteolytic degradation, leading to a loss of functionality and complications in downstream purification, is still a seriou...

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Bibliographic Details
Main Authors: Hehle Verena K, Paul Matthew J, Drake Pascal M, Ma Julian KC, van Dolleweerd Craig J
Format: Article
Language:English
Published: BMC 2011-12-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/11/128