In vitro mechanical vibration down-regulates pro-inflammatory and pro-fibrotic signaling in human vocal fold fibroblasts.

<h4>Introduction</h4>Voice rest following phonotrauma or phonosurgery has a considerable clinical impact, but clinical recommendations are inconsistent due to inconclusive data. As biopsies of the vocal folds (VF) for molecular biology studies in humans are unethical, we established a ne...

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Bibliographic Details
Main Authors: David Hortobagyi, Tanja Grossmann, Magdalena Tschernitz, Magdalena Grill, Andrijana Kirsch, Claus Gerstenberger, Markus Gugatschka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0241901