Hydrogen sulfide attenuates cigarette smoke-induced airway remodeling by upregulating SIRT1 signaling pathway

Hydrogen sulfide attenuates cigarette smoke-induced airway remodeling by upregulating SIRT1 signaling pathway

Airway remodeling is one of the characteristics for chronic obstructive pulmonary disease (COPD). The mechanism underlying airway remodeling is associated with epithelial-mesenchymal transition (EMT) in the small airways of smokers and patients with COPD. Sirtuin 1 (SIRT1) is able to reduce oxidativ...

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Bibliographic Details
Main Authors: Ruijuan Guan, Jian Wang, Zhou Cai, Ziying Li, Lan Wang, Yuanyuan Li, Jingyi Xu, Defu Li, Hongwei Yao, Wei Liu, Bingxian Deng, Wenju Lu
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231719308675

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http://www.sciencedirect.com/science/article/pii/S2213231719308675

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