Cerebellar long-term depression and auto-immune target of auto-antibodies: the concept of LTDpathies

Abstract There is general agreement that auto-antibodies against ion channels and synaptic machinery proteins can induce limbic encephalitis. In immune-mediated cerebellar ataxias (IMCAs), various synaptic proteins, such as GAD65, voltage-gated Ca channel (VGCC), metabotropic glutamate receptor type...

Full description

Bibliographic Details
Main Authors: Hiroshi Mitoma, Jerome Honnorat, Kazuhiko Yamaguchi, Mario Manto
Format: Article
Language:English
Published: Springer 2021-01-01
Series:Molecular Biomedicine
Subjects:
Online Access:https://doi.org/10.1186/s43556-020-00024-x