The Wnt-specific astacin proteinase HAS-7 restricts head organizer formation in Hydra

The Wnt-specific astacin proteinase HAS-7 restricts head organizer formation in Hydra

Abstract Background The Hydra head organizer acts as a signaling center that initiates and maintains the primary body axis in steady state polyps and during budding or regeneration. Wnt/beta-Catenin signaling functions as a primary cue controlling this process, but how Wnt ligand activity is locally...

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Bibliographic Details
Main Authors: Berenice Ziegler, Irene Yiallouros, Benjamin Trageser, Sumit Kumar, Moritz Mercker, Svenja Kling, Maike Fath, Uwe Warnken, Martina Schnölzer, Thomas W. Holstein, Markus Hartl, Anna Marciniak-Czochra, Jörg Stetefeld, Walter Stöcker, Suat Özbek
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Biology
Subjects:
Hydra
Wnt signaling
Proteinase
Astacin
Axis formation
Online Access:https://doi.org/10.1186/s12915-021-01046-9

Internet

https://doi.org/10.1186/s12915-021-01046-9

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