Poly- and autoreactivity of HIV-1 bNAbs: implications for vaccine design
Abstract A central puzzle in HIV-1 research is the inability of vaccination or even infection to reliably elicit humoral responses against broadly neutralizing epitopes in the HIV-1 envelope protein. In infected individuals, broadly neutralizing antibodies (bNAbs) do arise in a substantial minority,...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-07-01
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Series: | Retrovirology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12977-018-0435-0 |