Gaboxadol Normalizes Behavioral Abnormalities in a Mouse Model of Fragile X Syndrome

Fragile X syndrome (FXS) is the most common inherited form of intellectual disability and autism. FXS is also accompanied by attention problems, hyperactivity, anxiety, aggression, poor sleep, repetitive behaviors, and self-injury. Recent work supports the role of γ-aminobutyric-acid (GABA), the pri...

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Bibliographic Details
Main Authors: Patricia Cogram, Robert M. J. Deacon, Jennifer L. Warner-Schmidt, Melanie J. von Schimmelmann, Brett S. Abrahams, Matthew J. During
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnbeh.2019.00141/full