Sustained CD8+ T cell memory inflation after infection with a single-cycle cytomegalovirus.

Cytomegalovirus (CMV) is a β-herpesvirus that establishes a lifelong latent or persistent infection. A hallmark of chronic CMV infection is the lifelong persistence of large numbers of virus-specific CD8+ effector/effector memory T cells, a phenomenon called "memory inflation". How the vir...

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Bibliographic Details
Main Authors: Christopher M Snyder, Kathy S Cho, Elizabeth L Bonnett, Jane E Allan, Ann B Hill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3188546?pdf=render