REV-ERBα Regulates TH17 Cell Development and Autoimmunity

REV-ERBα Regulates TH17 Cell Development and Autoimmunity

Summary: RORγt is well recognized as the lineage-defining transcription factor for T helper 17 (TH17) cell development. However, the cell-intrinsic mechanisms that negatively regulate TH17 cell development and autoimmunity remain poorly understood. Here, we demonstrate that the transcriptional repre...

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Bibliographic Details
Main Authors: Mohammed Amir, Sweena Chaudhari, Ran Wang, Sean Campbell, Sarah A. Mosure, Laura B. Chopp, Qun Lu, Jinsai Shang, Oliver B. Pelletier, Yuanjun He, Christelle Doebelin, Michael D. Cameron, Douglas J. Kojetin, Theodore M. Kamenecka, Laura A. Solt
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718319077

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http://www.sciencedirect.com/science/article/pii/S2211124718319077

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