Statins Stimulate In Vitro Membrane FasL Expression and Lymphocyte Apoptosis through RhoA/ROCK Pathway in Murine Melanoma Cells

The capacity of FasL molecules expressed on melanoma cells to induce lymphocyte apoptosis contributes to either antitumor immune response or escape depending on their expression level. Little is known, however, about the mechanisms regulating FasL protein expression. Using the murine B16F10 melanom...

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Bibliographic Details
Main Authors: Guillaume Sarrabayrouse, Cindy Synaeve, Kevin Leveque, Gilles Favre, Anne-Françoise Tilkin-Manamé
Format: Article
Language:English
Published: Elsevier 2007-12-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558607801187