Structure-Functional Basis of Ion Transport in Sodium–Calcium Exchanger (NCX) Proteins

Structure-Functional Basis of Ion Transport in Sodium–Calcium Exchanger (NCX) Proteins

The membrane-bound sodium–calcium exchanger (NCX) proteins shape Ca2+ homeostasis in many cell types, thus participating in a wide range of physiological and pathological processes. Determination of the crystal structure of an archaeal NCX (NCX_Mj) paved the way for a thorough and systematic investi...

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Bibliographic Details
Main Authors: Moshe Giladi, Reut Shor, Michal Lisnyansky, Daniel Khananshvili
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:International Journal of Molecular Sciences
Subjects:
alternating access
NCX (sodium–calcium exchanger)
antiporter
transporter
occlusion
catalysis
selectivity
HDX-MS (hydrogen–deuterium exchange mass-spectrometry)
Online Access:http://www.mdpi.com/1422-0067/17/11/1949

Internet

http://www.mdpi.com/1422-0067/17/11/1949

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