The neurotrophic receptor Ntrk2 directs lymphoid tissue neovascularization during Leishmania donovani infection.
The neurotrophic tyrosine kinase receptor type 2 (Ntrk2, also known as TrkB) and its ligands brain derived neurotrophic factor (Bdnf), neurotrophin-4 (NT-4/5), and neurotrophin-3 (NT-3) are known primarily for their multiple effects on neuronal differentiation and survival. Here, we provide evidence...
Main Authors: | Jane E Dalton, Amy C Glover, Laura Hoodless, Eng-Kiat Lim, Lynette Beattie, Alun Kirby, Paul M Kaye |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-02-01
|
Series: | PLoS Pathogens |
Online Access: | https://doi.org/10.1371/journal.ppat.1004681 |
Similar Items
-
A Petri net model of granulomatous inflammation: implications for IL-10 mediated control of Leishmania donovani infection.
by: Luca Albergante, et al.
Published: (2013-01-01) -
Dynamic imaging of experimental Leishmania donovani-induced hepatic granulomas detects Kupffer cell-restricted antigen presentation to antigen-specific CD8 T cells.
by: Lynette Beattie, et al.
Published: (2010-03-01) -
Innate killing of Leishmania donovani by macrophages of the splenic marginal zone requires IRF-7.
by: Rebecca Phillips, et al.
Published: (2010-03-01) -
Cytokines and splenic remodelling during Leishmania donovani infection
by: Marcela Montes de Oca, et al.
Published: (2020-12-01) -
CD4+ Recent Thymic Emigrants Are Recruited into Granulomas during Leishmania donovani Infection but Have Limited Capacity for Cytokine Production.
by: John W J Moore, et al.
Published: (2016-01-01)