The neurotrophic receptor Ntrk2 directs lymphoid tissue neovascularization during Leishmania donovani infection.

The neurotrophic tyrosine kinase receptor type 2 (Ntrk2, also known as TrkB) and its ligands brain derived neurotrophic factor (Bdnf), neurotrophin-4 (NT-4/5), and neurotrophin-3 (NT-3) are known primarily for their multiple effects on neuronal differentiation and survival. Here, we provide evidence...

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Bibliographic Details
Main Authors: Jane E Dalton, Amy C Glover, Laura Hoodless, Eng-Kiat Lim, Lynette Beattie, Alun Kirby, Paul M Kaye
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1004681