Extracellular matrix rigidity modulates neuroblastoma cell differentiation and N-myc expression

<p>Abstract</p> <p>Neuroblastoma is a pediatric malignancy characterized by tremendous clinical heterogeneity, in which some tumors are extremely aggressive while others spontaneously differentiate into benign forms. Because the degree of differentiation correlates with prognosis,...

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Bibliographic Details
Main Authors: Umesh Vaibhavi, Cao Lizhi, Lam Wilbur A, Keung Albert J, Sen Shamik, Kumar Sanjay
Format: Article
Language:English
Published: BMC 2010-02-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/35