Artificial Inclusion Bodies for Clinical Development

Artificial Inclusion Bodies for Clinical Development

Abstract Bacterial inclusion bodies (IBs) are mechanically stable protein particles in the microscale, which behave as robust, slow‐protein‐releasing amyloids. Upon exposure to cultured cells or upon subcutaneous or intratumor injection, these protein materials secrete functional IB polypeptides, fu...

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Bibliographic Details
Main Authors: Julieta M. Sánchez, Hèctor López‐Laguna, Patricia Álamo, Naroa Serna, Alejandro Sánchez‐Chardi, Verónica Nolan, Olivia Cano‐Garrido, Isolda Casanova, Ugutz Unzueta, Esther Vazquez, Ramon Mangues, Antonio Villaverde
Format: Article
Language:English
Published: Wiley 2020-02-01
Series:Advanced Science
Subjects:
biomimetic materials
cancer
drug release
microparticles
recombinant proteins
Online Access:https://doi.org/10.1002/advs.201902420

Internet

https://doi.org/10.1002/advs.201902420

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