Quinpirole-Mediated Regulation of Dopamine D2 Receptors Inhibits Glial Cell-Induced Neuroinflammation in Cortex and Striatum after Brain Injury

Quinpirole-Mediated Regulation of Dopamine D2 Receptors Inhibits Glial Cell-Induced Neuroinflammation in Cortex and Striatum after Brain Injury

Brain injury is a significant risk factor for chronic gliosis and neurodegenerative diseases. Currently, no treatment is available for neuroinflammation caused by the action of glial cells following brain injury. In this study, we investigated the quinpirole-mediated activation of dopamine D2 recept...

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Bibliographic Details
Main Authors: Sayed Ibrar Alam, Min Gi Jo, Tae Ju Park, Rahat Ullah, Sareer Ahmad, Shafiq Ur Rehman, Myeong Ok Kim
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Biomedicines
Subjects:
brain injury
quinpirole
dopamine D2 receptors
glial cell
neuroinflammation
neurodegeneration
Online Access:https://www.mdpi.com/2227-9059/9/1/47

Internet

https://www.mdpi.com/2227-9059/9/1/47

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