Acute Psychological Stress Modulates the Expression of Enzymes Involved in the Kynurenine Pathway throughout Corticolimbic Circuits in Adult Male Rats

Tryptophan is an essential dietary amino acid that is necessary for protein synthesis, but also serves as the precursor for serotonin. However, in addition to these biological functions, tryptophan also serves as a precursor for the kynurenine pathway, which has neurotoxic (quinolinic acid) and neur...

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Bibliographic Details
Main Authors: Haley A. Vecchiarelli, Chaitanya P. Gandhi, Matthew N. Hill
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2016/7215684