Modulation of Cytokine Production by Drugs with Antiepileptic or Mood Stabilizer Properties in Anti-CD3- and Anti-CD40-Stimulated Blood In Vitro

Increased cytokine production possibly due to oxidative stress has repeatedly been shown to play a pivotal role in the pathophysiology of epilepsy and bipolar disorder. Recent in vitro and animal studies of valproic acid (VPA) report antioxidative and anti-inflammatory properties, and suppression of...

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Bibliographic Details
Main Authors: Hubertus Himmerich, Stefanie Bartsch, Hajo Hamer, Roland Mergl, Jeremias Schönherr, Charlotte Petersein, Alexander Munzer, Kenneth Clifford Kirkby, Katrin Bauer, Ulrich Sack
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2014/806162