Neuroprotective mechanism of Kai Xin San: upregulation of hippocampal insulin-degrading enzyme protein expression and acceleration of amyloid-beta degradation

Neuroprotective mechanism of Kai Xin San: upregulation of hippocampal insulin-degrading enzyme protein expression and acceleration of amyloid-beta degradation

Kai Xin San is a Chinese herbal formula composed of Radix Ginseng , Poria , Radix Polygalae and Acorus Tatarinowii Rhizome . It has been used in China for many years for treating amnesia. Kai Xin San ameliorates amyloid-β (Aβ)-induced cognitive dysfunction and is neuroprotective in vivo , but its pr...

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Bibliographic Details
Main Authors: Na Wang, Yong-ming Jia, Bo Zhang, Di Xue, Maharjan Reeju, Yan Li, Shu-ming Huang, Xue-wei Liu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; neurodegeneration; traditional Chinese medicine; Kai Xin San; insulin-degrading enzyme; amyloid-β; Alzheimer′s disease; Chinese herbal compound; Aβ-degrading enzymes; neurons; Radix Ginseng; Radix Polygalae; Acorus Tatarinowii Rhizoma; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=4;spage=654;epage=659;aulast=Wang

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=4;spage=654;epage=659;aulast=Wang

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