The Plasmid-Borne tet(A) Gene Is an Important Factor Causing Tigecycline Resistance in ST11 Carbapenem-Resistant Klebsiella pneumoniae Under Selective Pressure

The Plasmid-Borne tet(A) Gene Is an Important Factor Causing Tigecycline Resistance in ST11 Carbapenem-Resistant Klebsiella pneumoniae Under Selective Pressure

The emergence and prevalence of tigecycline-resistant Klebsiella pneumoniae have seriously compromised the effectiveness of antimicrobial agents in the treatment of infections. To explore the role of the plasmid-borne tet(A) gene in tigecycline resistance in carbapenem-resistant K. pneumoniae (CRKP)...

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Bibliographic Details
Main Authors: Juan Xu, Zhongliang Zhu, Yanmin Chen, Weizhong Wang, Fang He
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Microbiology
Subjects:
mutation
plasmid-bearing
tigecycline
tet(A)
Klebsiella pneumoniae
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.644949/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2021.644949/full

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