Targeted anti-staphylococcal therapy with endolysins in atopic dermatitis and the effect on steroid use, disease severity and the microbiome: study protocol for a randomized controlled trial (MAAS trial)

Targeted anti-staphylococcal therapy with endolysins in atopic dermatitis and the effect on steroid use, disease severity and the microbiome: study protocol for a randomized controlled trial (MAAS trial)

Abstract Background Atopic dermatitis (AD) is associated with reduced skin microbial diversity and overgrowth of Staphylococcus (S.) aureus. However, the importance of S. aureus colonisation in the complex pathogenesis remains unclear and studies on the effect of anti-staphylococcal therapy in non-i...

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Bibliographic Details
Main Authors: Joan Totté, Jill de Wit, Luba Pardo, Frank Schuren, Martijn van Doorn, Suzanne Pasmans
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Trials
Subjects:
Atopic dermatitis
Eczema
Staphylococcus aureus
Endolysins
Lysins
Staphefekt
Online Access:http://link.springer.com/article/10.1186/s13063-017-2118-x

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http://link.springer.com/article/10.1186/s13063-017-2118-x

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