Histamine Is an Inducer of the Heat Shock Response in SOD1-G93A Models of ALS

Histamine Is an Inducer of the Heat Shock Response in SOD1-G93A Models of ALS

(1) Background: Amyotrophic lateral sclerosis (ALS) is a multifactorial non-cell autonomous disease where activation of microglia and astrocytes largely contributes to motor neurons death. Heat shock proteins have been demonstrated to promote neuronal survival and exert a strong anti-inflammatory ac...

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Bibliographic Details
Main Authors: Savina Apolloni, Francesca Caputi, Annabella Pignataro, Susanna Amadio, Paola Fabbrizio, Martine Ammassari-Teule, Cinzia Volonté
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
dendritic spines
heat shock proteins
histamine
microglia
motor neurons
SOD1-G93A
Online Access:https://www.mdpi.com/1422-0067/20/15/3793

Internet

https://www.mdpi.com/1422-0067/20/15/3793

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