Caveolin-3 differentially orchestrates cholinergic and serotonergic constriction of murine airways

Abstract The mechanisms of controlling airway smooth muscle (ASM) tone are of utmost clinical importance as inappropriate constriction is a hallmark in asthma and chronic obstructive pulmonary disease. Receptors for acetylcholine and serotonin, two relevant mediators in this context, appear to be in...

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Bibliographic Details
Main Authors: M. Keshavarz, M. Skill, M. I. Hollenhorst, S. Maxeiner, M. Walecki, U. Pfeil, W. Kummer, G. Krasteva-Christ
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25445-1