Effects of decitabine on allogeneic immune reactions of donor lymphocyte infusion via activation of dendritic cells

Effects of decitabine on allogeneic immune reactions of donor lymphocyte infusion via activation of dendritic cells

Abstract Background Successful prevention of post-transplantation relapse after donor lymphocyte infusion (DLI) depends on its capability to mediate an effective graft-versus-leukemia (GVL) response while minimizing DLI-related toxicity, including graft-versus-host disease (GVHD). Methods We assesse...

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Bibliographic Details
Main Authors: Yong-Rim Kwon, Hye Joung Kim, Min-Jung Sohn, Ji-Young Lim, Kyung-Shin Park, Seok Lee, Nack-Gyun Chung, Dae-Chul Jeong, Chang-Ki Min, Yoo-Jin Kim
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Experimental Hematology & Oncology
Subjects:
Donor lymphocyte infusion
Decitabine
Graft-versus-host disease
Graft-versus-leukemia effect
Dendritic cells
Online Access:http://link.springer.com/article/10.1186/s40164-020-00178-y

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http://link.springer.com/article/10.1186/s40164-020-00178-y

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