Maternal Folate Status and the BHMT c.716G>A Polymorphism Affect the Betaine Dimethylglycine Pathway during Pregnancy

Maternal Folate Status and the BHMT c.716G>A Polymorphism Affect the Betaine Dimethylglycine Pathway during Pregnancy

The effect of the betaine: homocysteine methyltransferase BHMT c.716G>A (G: guanosine; A: adenosine) single nucleotide polymorphism (SNP) on the BHMT pathway is unknown during pregnancy. We hypothesised that it impairs betaine to dimethylglycine conversion and that folate status modifies its...

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Bibliographic Details
Main Authors: Jose M. Colomina, Pere Cavallé-Busquets, Sílvia Fernàndez-Roig, Pol Solé-Navais, Joan D. Fernandez-Ballart, Mónica Ballesteros, Per M. Ueland, Klaus Meyer, Michelle M. Murphy
Format: Article
Language:English
Published: MDPI AG 2016-10-01
Series:Nutrients
Subjects:
pregnancy
folate
betaine: homocysteine methyltransferase
BHMT c.716G&gt
A
betaine
dimethylglycine
Online Access:http://www.mdpi.com/2072-6643/8/10/621

Internet

http://www.mdpi.com/2072-6643/8/10/621

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