An Integrated Analysis of C5AR2 Related to Malignant Properties and Immune Infiltration of Breast Cancer

BackgroundC5AR2 (GPR77, C5L2) is the second receptor for C5a that is a potent protein generated by complement activation. C5AR2 can mediate its own signaling events and exert significant immunomodulatory effects through those events. However, research of C5AR2 in cancer is limited, and its function...

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Bibliographic Details
Main Authors: Yumeng Zhu, Xiaochao Wang, Yanqing Xu, Lu Chen, Peipei Ding, Jianfeng Chen, Weiguo Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.736725/full