Reference-free SNP calling: improved accuracy by preventing incorrect calls from repetitive genomic regions

Reference-free SNP calling: improved accuracy by preventing incorrect calls from repetitive genomic regions

<p>Abstract</p> <p>Background</p> <p>Single nucleotide polymorphisms (SNPs) are the most abundant type of genetic variation in eukaryotic genomes and have recently become the marker of choice in a wide variety of ecological and evolutionary studies. The advent of next-g...

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Bibliographic Details
Main Authors: Dou Jinzhuang, Zhao Xiqiang, Fu Xiaoteng, Jiao Wenqian, Wang Nannan, Zhang Lingling, Hu Xiaoli, Wang Shi, Bao Zhenmin
Format: Article
Language:English
Published: BMC 2012-06-01
Series:Biology Direct
Subjects:
Next-generation sequencing
single nucleotide polymorphism
genotyping
maximum likelihood
mixed Poisson/normal model
Online Access:http://www.biology-direct.com/content/7/1/17

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http://www.biology-direct.com/content/7/1/17

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