The immortal strand hypothesis: still non-randomly segregating opinions

Cairns first suggested a mechanism for protecting the genomes of stem cells (SCs) from replicative errors some 40 years ago when he proposed the immortal strand hypothesis, which argued for the inheritance of a so-called immortal strand by an SC following asymmetric SC divisions. To date, the existe...

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Bibliographic Details
Main Authors: Wakeman Jane A., Hmadcha Abdelkrim, Soria Bernat, McFarlane Ramsay J.
Format: Article
Language:English
Published: De Gruyter 2012-06-01
Series:Biomolecular Concepts
Subjects:
Online Access:https://doi.org/10.1515/bmc-2011-0053