The Anti-Tumor Effects of Adipose Tissue Mesenchymal Stem Cell Transduced with HSV-Tk Gene on U-87-Driven Brain Tumor.

The Anti-Tumor Effects of Adipose Tissue Mesenchymal Stem Cell Transduced with HSV-Tk Gene on U-87-Driven Brain Tumor.

Glioblastoma (GBM) is an infiltrative tumor that is difficult to eradicate. Treating GBM with mesenchymal stem cells (MSCs) that have been modified with the HSV-Tk suicide gene has brought significant advances mainly because MSCs are chemoattracted to GBM and kill tumor cells via a bystander effect....

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Bibliographic Details
Main Authors: Suely Maymone de Melo, Simone Bittencourt, Enéas Galdini Ferrazoli, Clivandir Severino da Silva, Flavia Franco da Cunha, Flavia Helena da Silva, Roberta Sessa Stilhano, Priscila Martins Andrade Denapoli, Bianca Ferrarini Zanetti, Priscila Keiko Matsumoto Martin, Leonardo Martins Silva, Adara Aurea dos Santos, Leandra Santos Baptista, Beatriz Monteiro Longo, Sang Won Han
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4467037?pdf=render

Internet

http://europepmc.org/articles/PMC4467037?pdf=render

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