Aqueous Extract of Pomegranate Alone or in Combination with Citalopram Produces Antidepressant-Like Effects in an Animal Model of Menopause: Participation of Estrogen Receptors

Aqueous Extract of Pomegranate Alone or in Combination with Citalopram Produces Antidepressant-Like Effects in an Animal Model of Menopause: Participation of Estrogen Receptors

It has been reported that the aqueous extract of pomegranate (AE-PG) has polyphenols with estrogenic-like activities. The present work determines if AE-PG alone or in combination with the selective serotonin reuptake inhibitor, citalopram, has antidepressant-like effects. It was also analyzed the pa...

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Bibliographic Details
Main Authors: Brenda Valdés-Sustaita, Carolina López-Rubalcava, María Eva González-Trujano, Cristina García-Viguera, Erika Estrada-Camarena
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:International Journal of Molecular Sciences
Subjects:
pomegranate fruit
citalopram
ovariectomy
antidepressant-like action
estrogen receptors
polyphenols
Online Access:https://www.mdpi.com/1422-0067/18/12/2643

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https://www.mdpi.com/1422-0067/18/12/2643

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