CD3+CD4+gp130+ T Cells Are Associated With Worse Disease Activity in Systemic Lupus Erythematosus Patients

CD3+CD4+gp130+ T Cells Are Associated With Worse Disease Activity in Systemic Lupus Erythematosus Patients

The receptors for IL-35, IL-12Rβ2 and gp130, have been implicated in the inflammatory pathophysiology of autoimmune diseases. In this study, we set out to investigate the serum IL-35 levels and the surface levels of IL-12Rβ2 and gp130 in CD3+CD4+, CD3+CD4─ and CD3─CD4─ lymphocyte subpopulations in s...

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Bibliographic Details
Main Authors: Nur Diyana Mohd Shukri, Aziz Farah Izati, Wan Syamimee Wan Ghazali, Che Maraina Che Hussin, Kah Keng Wong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
systemic lupus erythematosus
gp130
IL6ST
IL-35
IL-12Rβ2
SLEDAI-2K
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.675250/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.675250/full

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