Heat shock inhibits lipopolysaccharide-induced tissue factor activity in human whole blood

<p>Abstract</p> <p>Background</p> <p>During gram-negative sepsis, lipopolysaccharide (LPS) induces tissue factor expression on monocytes. The resulting disseminated intravascular coagulation leads to tissue ischemia and worsens the prognosis of septic patients. There ar...

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Bibliographic Details
Main Authors: Thielmann Matthias, Zacharowski Kai, Sucker Christoph, Hartmann Matthias
Format: Article
Language:English
Published: BMC 2007-09-01
Series:Thrombosis Journal
Online Access:http://www.thrombosisjournal.com/content/5/1/13