Regulation of AMP-activated protein kinase by natural and synthetic activators

Regulation of AMP-activated protein kinase by natural and synthetic activators

The AMP-activated protein kinase (AMPK) is a sensor of cellular energy status that is almost universally expressed in eukaryotic cells. While it appears to have evolved in single-celled eukaryotes to regulate energy balance in a cell-autonomous manner, during the evolution of multicellular animals i...

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Bibliographic Details
Main Author: David Grahame Hardie
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Acta Pharmaceutica Sinica B
Subjects:
AMP-activated protein
kinase
Energy balance
AMP
AMPK activator
Mitochondrial function
Regulatory mechanism
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383515000891

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http://www.sciencedirect.com/science/article/pii/S2211383515000891

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