Highlighting the DNA damage response with ultrashort laser pulses in the near infrared and kinetic modeling

Highlighting the DNA damage response with ultrashort laser pulses in the near infrared and kinetic modeling

Our understanding of the mechanisms governing the response to DNA damage in higher eucaryotes crucially depends on our ability to dissect the temporal and spatial organization of the cellular machinery responsible for maintaining genomic integrity. To achieve this goal, we need experimental tools to...

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Bibliographic Details
Main Authors: Elisa eFerrando-May, Martin eTomas, Philipp eBlumhardt, Martin eStöckl, Matthias eFuchs, Alfred eLeitenstorfer
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Genetics
Subjects:
DNA Repair
Photochemistry
Nonlinear optics
Fluorescence Imaging
chromatin dynamics
DNA strand breaks
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00135/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00135/full

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