Deregulation of the Replisome Factor MCMBP Prompts Oncogenesis in Colorectal Carcinomas through Chromosomal Instability
Genetic instability has emerged as an important hallmark of human neoplasia. Although most types of cancers exhibit genetic instability to some extent, in colorectal cancers genetic instability is a distinctive characteristic. Recent studies have shown that deregulation of genes involved in sister...
Main Authors: | Mauricio Quimbaya, Eric Raspé, Geertrui Denecker, Bram De Craene, Ria Roelandt, Wim Declercq, Xavier Sagaert, Lieven De Veylder, Geert Berx |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-09-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558614001055 |
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