Deregulation of the Replisome Factor MCMBP Prompts Oncogenesis in Colorectal Carcinomas through Chromosomal Instability

Genetic instability has emerged as an important hallmark of human neoplasia. Although most types of cancers exhibit genetic instability to some extent, in colorectal cancers genetic instability is a distinctive characteristic. Recent studies have shown that deregulation of genes involved in sister...

Full description

Bibliographic Details
Main Authors: Mauricio Quimbaya, Eric Raspé, Geertrui Denecker, Bram De Craene, Ria Roelandt, Wim Declercq, Xavier Sagaert, Lieven De Veylder, Geert Berx
Format: Article
Language:English
Published: Elsevier 2014-09-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558614001055