Erythropoietin amplifies stroke-induced oligodendrogenesis in the rat.

Erythropoietin (EPO), a hematopoietic cytokine, enhances neurogenesis and angiogenesis during stroke recovery. In the present study, we examined the effect of EPO on oligodendrogenesis in a rat model of embolic focal cerebral ischemia.Recombinant human EPO (rhEPO) at a dose of 5,000 U/kg (n = 18) or...

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Bibliographic Details
Main Authors: Li Zhang, Michael Chopp, Rui Lan Zhang, Lei Wang, Jing Zhang, Ying Wang, Yier Toh, Manoranjan Santra, Mei Lu, Zheng Gang Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2884017?pdf=render