Detection of necroptosis by phospho-MLKL immunohistochemical labeling

Summary: TNF-induced necroptosis is involved in many physiological and pathological processes. Phospho-MLKL is a hallmark of necroptosis. Cecum is a sensitive organ with extensive necroptosis responses to TNF in vivo. Here, taking advantage of commercially available mouse TNF and easily accessible r...

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Bibliographic Details
Main Authors: Peng He, Tingting Ai, Zhang-Hua Yang, Jianfeng Wu, Jiahuai Han
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166720302380